Scientific projects Research Fund, MES
Infrastructure projects MES
Scientific Project, MU-Sofia
Project number/Contract (year of funding) | Project Name | Head |
Contract КП-06-ОПР 03/17 (2018) | Investigation of the role of germinal and somatic genomic changes on the development of multiple primary tumors | Acad. prof. Chavdar Krumov Slavov, MD, D.Sc. |
Contract КП-06-Н23/9 (2018) | Somatic changes in the most common benign (nodular goiter) and malignant (papillary thyroid carcinoma) thyroid tumors | Chief Assit. Kalin Nikolaev Vidinov, MD |
Contract № ДН13/12 (2017) | Study of the regulation of neoangiogenesis in advanced laryngeal carcinoma | Assoc. Prof. Todor Miroslavov Popov, MD |
Contract № ДН03/14 (2016) | MicroRNA profiling in adenocarcinomas and squamous cell carcinomas of the lung in Bulgarian patients | Prof. Radka Petrova Kaneva, PhD |
Contract № ДФНИ-Б02/6 (2014) | Genetic study of endophenotypes in bipolar disorder | Prof. Vihra Krumova Milanova-Nesheva, MD, D.Sc. |
Contract № ДФНИ-Б02/3 (2014) | Hereditary cerebellar ataxias - molecular epidemiology in the Bulgarian population and search for new forms | Prof. Ivaylo Liudmilov Tarnev, MD, D.Sc. |
Contract № ДФНИ-Б01/27 (2012) | Genomic and exomatic associative research in heroin addiction in Bulgaria | Prof. Ivo Marinov Kremenski, MD, D.Sc. |
Contract № ДФНИ-Б01/28 (2012) | Expression profiling of miRNAs in Bulgarian patients with prostate cancer and development of a panel of biomarkers for diagnosis and prognosis | Prof. Radka Petrova Kaneva, PhD |
Contract № ДМУ 03/73 (2011) | Genomic analysis for mutations in patients with congenital abnormalities of the kidneys and urinary tract (CAKUT) | Chief Assist. Olga Zhivanova Beltcheva, PhD |
Contract № ДДВУ 02/35 (2010) | Monitoring of circulating tumor cell (CTC) levels in patients with metastatic breast cancer - prognostic and predictive significance | Assoc. Prof. Atanaska Velichkova Mitkova, PhD |
Contract № ДДВУ 02/33 (2010) | Analysis of the clinical and molecular characteristics of squamous cell carcinoma of the larynx and their applicability to determine the prognosis and efficacy of treatment | Teodora Evgenieva Goranova, PhD |
Contract № ДО12-7 (2010) | Modern approach for diagnosis and determination of the frequency of genotypic-phenotypic correlations in patients with gestational diabetes mellitus in Bulgaria | Assoc. Prof. Iliyana Borisova Atanasova, MD |
Contract № ДТК02-49 (2009 ) | Clinical and molecular markers with prognostic value for survival, quality of life and efficacy of treatment in malignant glial tumors | Prof. Nikolay Stefanov Gabrovski, MD |
Contract № ДТК 02/67 (2009) | Modern approaches to discovering the genetic basis of epilepsy | Prof. Albena Kirilova Yordanova, PhD |
Contract № ДТК02-51 (2009) | Complete genome screening for copy number variantions in mental retardation | Assoc. Prof. Veneta Sashova Bozhinova-Chamova, MD |
Contract № ДОО2_119 (2009) | Study of genetic variants associated with increased risk and search for diagnostic and prognostic expression markers in prostate cancer | Acad. prof. Chavdar Krumov Slavov, MD, D.Sc. |
Contract Д002-310 (2008) | Molecular pathways involved in breast cancer | Prof. Elena Ivanova Georgieva, PhD |
Contract ВУ-Л-317 (2007) | Modern approach for diagnosis and study of hereditary mevromuscular diseases in Bulgaria - application of scientific knowledge for the benefit of the patient | Prof. Ivaylo Liudmilov Tarnev, MD, D.Sc. |
Project Number / Contract (year of funding) | Project Name | Head |
FP6-ACC-SSA- 017147, (2005-2008), INCO | MMCBG enhancing the capacity of biomedical рesearch in Bulgaria | Prof. Ivo Marinov Kremenski, MD, D.Sc. |
DRI15/ 2006 (2006-2008) | Establishment of a sector for SNP genotyping and gene expression in MMC, MU-Sofia | Acad. prof. Vladimir Atanasov Ovcharov, MD, D.Sc. |
CVP01/0123 (2008-2010), Contract DO02-118 (2008) | Increasing the research potential of MU-Sofia by establishing a collaborative, multidisciplinary Molecular Medicine Center as the main national infrastructure in the field of biobanking, functional genomics, proteomics and metabolomics | Acad. prof. Vanyo Ivanov Mitev, MD, D.Sc. |
URC_09_003/ 2009, Contract DUNK 01/2/2009 (2009-2019) | The National University Complex for Biomedical and Translational Research | Acad. prof. Vanyo Ivanov Mitev, MD, D.Sc. |
8I/ 2009 (2009-2010) | Increasing the capacity of scientific units in Cell and Tissue Cultivation, Microarray Analysis and Laser Microdissection of the Center for Molecular Medicine, MU-Sofia | Acad. prof. Vanyo Ivanov Mitev, MD, D.Sc. |
Д01-285/17.12.2019 | “National University Complex for Biomedical and Translational Research, linked to participation in BBMRI-ERIC (NUCBTR and BBMRI.bg) Program” National Roadmap of Research Infrastructures 2017-2023”, MES | Acad.Prof. V.Mitev |
Д01-395/18.10.2020 | “National University Complex for Biomedical and Translational Research, linked to participation in BBMRI-ERIC (NUCBTR and BBMRI.bg) Program” National Roadmap of Research Infrastructures 2020-2027”, MES | Acad.Prof. V.Mitev |
Project Number / Contract (year of funding) | Project Name | Head |
Contract №Д-148 (2019) | Molecular genetic analysis for mutations in the TERT, BRAF and NRAS genes in patients with papillary thyroid carcinoma | Prof. Radka Petrova Kaneva, PhD |
Contract №Д-144 (2019) | TP53 мутационен статус при не-дребноклетъчен белодробен карцином | Вероника Йорданова Петкова, MSc |
Contract №Д-142 (2019) | Study of rs2736340 polymorphisms in the FAM167A-BLK region as a factor in the development of dermatomyositis in adults | Yoana Vladimirova Pozharashka, MD |
Contract №Д-138 (2019) | Investigation of genetic identity between laryngeal carcinoma and cervical metastases | Venelin Marinov Marinov, MD |
Contract №Д-135 (2019) | Study of rare variants in genes encoding ion channels and their association in patients with bipolar disorder and schizophrenia | Radosveta Dimitrova Bozhilova, MSc |
Contract №Д-126 (2019) | Genetic bases of cardiomyopathies in patients of Bulgarian origin | Monika Ivanova Shumkova, MD |
Contract №Д-116 (2019) | Genetic analysis for mutations in the UMOD gene to detect autosomal dominant tubulo interstitial kidney disease | Assoc. Prof. Mariya Simeonova Gaydarova, MD |
Contract №Д-109 (2019) | Establishment of a biobank for fecal microbiota for the purpose of safe and effective transplantation of fecal microbiota in Bulgaria | Assoc. Prof. Ventzislav Nakov Nakov, MD |
Contract №Д-104 (2019) | Study of polymorphisms rs2279115, rs956572 in the Bcl2 gene as a factor in the development of dermatomyositis in adults | Assoc. Prof. Liubomir Asenov Durmishev, MD |
Contract №Д-73 (2019) | Genetic factors causing changes in the normal function of the complement system and related renal impairment | Chief Assist. Olga Zhivanova Beltcheva, PhD |
Contract №Д-70 (2019) | Analysis of somatic mutations in primary tumors with different localization in patients with multiple primary neoplasia | Assoc. Prof. Atanaska Velichkova Mitkova, PhD |
Contract №Д-232 (2018) | Intestinal carriers of broad-spectrum beta-lactamase and / or carbapenemase - producing Enterbacteriaceace in hospitalized, outpatients and healthy people - children and adults | Assoc. Prof. Rumyana Donkova Markovska-Davidkova, MD |
Contract №Д-135 (2018) | Frequency and spectrum of mutations in the PIK3CA gene in the Bulgarian population of breast cancer patients | Slavyana Slavcheva Usheva, MD |
Contract №Д-134 (2018) | Expression analysis of key genes associated with immune response avoidance in lung cancer | Veronika Yordanova Petkova, MSc |
Contract №Д-131 (2018) | Study of rare variants in SHANK1 and SHANK2 genes and their association with bipolar disorder and schizophrenia in Bulgarian patients | Radosveta Dimitrova Bozhilova, MSc |
Contract №Д-123 (2018) | Genetic expression analysis of selected genes and comparison with serum levels of their products in Bulgarian patients with benign thyroid nodules and papillary thyroid carcinoma | Inna Dimitrova Dimitrova, MD |
Contract №Д-115 (2018) | Analysis for promoter hypermethylation of tumor suppressor genes in ovarian carcinoma | Assoc. Prof. Rumen Georgiev Dimitrov, MD |
Contract №Д-109 (2018) | Identification of gene mutations leading to retinal degeneration in Bulgarian patients by next generation sequencing of target genes | Prof. Silvia Zdravkova Cherninkova-Gopina, MD, D.Sc. |
Contract №Д-73 (2018) | Genetic factors and clinical characteristics of vascular complications in Bulgarian patients with type 2 diabetes mellitus | Prof. Radka Petrova Kaneva, PhD |
Contract №Д-72 (2018) | Promoter hypermethylation of tumor suppressor genes in patients with breast cancer | Prof. Svetlana Liubomirova Hristova, MD, D.Sc. |
Contract №Д-71 (2018) | Study of the role of genes associated with familial cancer syndromes on the development of multiple primary tumors | Assoc. Prof. Atanaska Velichkova Mitkova, PhD |
Contract №Д-62 (2018) | miRNA predictive profile for risk assessment of cardiovascular complications in type 2 diabetes mellitus | Prof. Ivanka Istalianova Dimova, MD |
Contract №Д-59 (2018) | Next generation sequencing of target genes for identification of genetic mutations in Bulgarian patients with familial forms of hematuria | Chief Assist. Olga Zhivanova Beltcheva, PhD |
Contract №Д-54 (2018) | Study of the mechanisms of chromosomal and plasmid quinolone resistance in third generation cephalosporins and / or carbapenem-resistant clinically significant isolates of Klebsiella spp at Sveta Marina University Hospital Varna | Assoc. Prof. Rumyana Donkova Markovska-Davidkova, MD |
Contract №Д-123 (2017) | Study of methotrexate drug-related genetic polymorphisms in patients with adolescent idiopathic arthritis | Assoc. Prof. Stefan Nedev Stefanov, MD |
Contract №Д-115 (2017) | Study of the polymorphisms rs1799782 and rs25487 in the XRCC1 gene as factors for the development of dermatomyositis in adults | Assoc. Prof. Liubomir Asenov Durmishev, MD |
Contract №Д-77 (2017) | Study of copy number variants in patients with Parkinson's disease | Prof. Albena Kirilova Yordanova, PhD |
Contract №Д-75 (2017) | Clarification of the role of selected polymorphic variants in genes associated with blood pressure values in relation to the risk of developing ischemic heart disease | Prof. Radka Petrova Kaneva, PhD |
Contract №Д-70 (2017) | Influence of the rs266729 promoter polymorphism on the transcriptional regulation of the adiponectin gene (ADIPOQ) in normal pregnancy and gestational diabetes | Chief Assist. Olga Zhivanova Beltcheva, PhD |
Contract №Д-69 (2017) | Post-vaccine effect of 10-valent pneumococcal conjugate vaccine (PHiD-PCV10) on the etiology of acute otitis media (AOM) and carrier of otopathogenic bacteria in children with AOM in 2015-2016 | Prof. Lena Petrova Sechanova, MD |
Contract №Д-62 (2017) | Next generation sequencing of patients with hereditary neurosensory hearing loss to clarify the genetic cause of hearing loss | Prof. Diana Petrova Popova, MD, D.Sc. |
Contract №Д-59 (2017) | Study of the main mechanisms of resistance to beta-lactams and quinolones in third-generation cephalosporin-resistant and / or carbapenems clinically significant isolates of Enterobacter spp at the University Hospital "St. Marina" Varna | Assoc. Prof. Rumyana Donkova Markovska-Davidkova, MD |
Contract №Д-144 (2017) | Expression of androgen receptor in association with other prognostic and predictive factors in Bulgarian breast cancer patients | Slavyana Slavcheva Usheva, MD |
Contract №Д-138 (2017) | Molecular profiling of the main histological types of lung carcinomas | Veronika Yordanova Petkova, MSc |
Contract №Д-137 (2017) | Investigation of the role of hypoxic microRNAs in laryngeal carcinoma | Silva Garo Kyurkchiyan, PhD |
Contract №Д-132 (2017) | Evaluation of the importance of a panel of somatic mutations as prognostic factors in gastric cancer | Angel Nikolaev Arabadzhiev, MD |
Contract №97 (2016) | Expansion of the biobank from patients with ovarian cancer and optimization of the conditions for storage of biological materials | Assoc. Prof. Rumen Georgiev Dimitrov, MD |
Contract №96 (2016) | Tissue storage to further expand tissue, plasma and DNA bank of breast cancer patients | Assoc. Prof. Teofil Angelov Sedloev, MD |
Contract №90 (2016) | Plasma miRNA expression analysis in patients with non-small cell lung carcinomas and obstructive pulmonary disease | Assoc. prof. Yanina Georgieva Slavova-Marinova, MD |
Contract №83 (2016) | Non-classical forms of 21-hydroxylase deficiency: clinical and molecular genetic diagnosis | Prof. Iva Hristova Stoeva, MD |
Contract №81 (2016) | Epigenetic biomarkers in Bulgarian patients with esophageal tumors | Assoc. Prof. Oleg Georgiev Cholakov, MD |
Contract №76 (2016) | Expression analysis of plasma microribonucleic acids in patients with rheumatoid arthritis and determination of their diagnostic and prognostic value | Prof. Zlatimir Gospodinov Kolarov, MD, D.Sc. |
Contract №75 (2016) | Determination of diagnostic and prognostic value of microribonucleic acids in plasma in patients with systemic lupus erythematosus | Assoc. Prof. Simeon Valentinov Monov, MD |
Contract №67 (2016) | Study of the relationship between IL-17 polymorphisms rs2275913 and serum IL-17 levels - factors for the development of dermatomyositis in adults | Assoc. Prof. Liubomir Asenov Durmishev, MD |
Contract №63 (2016) | Study of the role of pharmacogenetic factors in refining drug therapy with tacrolimus in patients with kidney transplantation in Bulgaria | Prof. Emil Paskalev Dimitrov, MD, D.Sc. |
Contract №35 (2016) | Confirmatory analysis of potentially pathogenic variants in Parkinson's disease-related genes found through next generation sequencing | Prof. Albena Kirilova Yordanova, PhD |
Contract №30 (2016) | Genetic profiling of laryngeal carcinoma by next generation sequencing | Prof. Diana Petrova Popova, MD, D.Sc. |
Contract №29 (2016) | Molecular markers of diagnostic and prognostic value in the treatment of solid tumors in childhood | Prof. Radka Petrova Kaneva, PhD |
Contract №27 (2016) | Analysis of somatic mutations in Bulgarian patients with colorectal and gastric carcinomas by next generation sequencing of a panel of tumor-associated genes | Prof. Georgi Todorov Todorov, MD |
Contract №26 (2016) | Associative analysis of polymorphic markers in or near selected candidate genes associated with predisposition to arterial hypertension in Bulgarians | Prof. Kiril Liubenov Naydenov, PhD |
Contract №24 (2016) | Analysis of somatic mutations in the main histological types of lung carcinomas: PC, AK, NET (CT, DKBD and ECNE) in a group of Bulgarian patients by next generation sequencing of a panel of tumor-associated genes | Assoc. Prof. Atanaska Velichkova Mitkova, PhD |
Contract №12-Д (2016) | Expression analysis of an expanded panel of selected hypoxic microRNAs in patients diagnosed with laryngeal cancer in tissue and plasma samples | Silva Garo Kyurkchiyan, PhD |
Contract №11-Д (2016) | Expression analysis of Toll-like receptor 2 (TLR2), Toll-like receptor 4 (TLR4) and Toll-like receptor 7 (TLR7) in patients with chronic purulent otitis and chronic rhinosinusitis | Stoyan Ivanov Dimitrov, MD |
Contract №8-Д (2016) | Next generation sequencing by synthesis in selected patients with different characteristics of congenital anomalies of the kidneys and urinary tract (CAKUT) | Valentin Martinov Penchev, MSc |
Contract №6-Д (2016) | Mutations in the gene encoding hTPO among clinically selected Bulgarian patients with primary congenital hypothyroidism | Boris Georgiev Stoilov |
Contract №5-Д (2016) | Quantitative real-time PCR of chromosomal microaberrations detected in patients with complex epileptic syndromes using microarray technology | Valentina Liubenova Peycheva, PhD |
Contract №68 (2015) | Analysis of polymorphic variants in candidate genes associated with response to methotrexate therapy in children with juvenile idiopathic arthritis | Assoc. Prof. Stefan Nedev Stefanov, MD |
Contract №66 (2015) | Genetic changes in primary glioblastomas and their relationship with the prognosis in Bulgarian patients | Prof. Nikolay Stefanov Gabrovski, MD |
Contract №62 (2015) | Expression analysis of serum microribonucleic acids and determination of their diagnostic and prognostic value in patients with progressive systemic sclerosis | Prof. Zlatimir Gospodinov Kolarov, MD, D.Sc. |
Contract №61 (2015) | Next diagnostic and prognostic biomarkers in rheumatoid arthritis | Assoc. Prof. Simeon Valentinov Monov, MD |
Contract №55 (2015) | Role of promoter hypermethylation in the CD3Z gene for the etiology and pathogenesis of dermatomyositis | Assoc. Prof. Liubomir Asenov Durmishev, MD |
Contract №50 (2015) | Next generation sequencing of target genes for retinal degeneration in Bulgarian patients | Prof. Silvia Zdravkova Cherninkova-Gopina, MD, D.Sc. |
Contract №24 (2015) | Development of a non-invasive method for assessment of the implantation potential of human embryos based on the expression of miRNAs in the culture medium | Prof. Radka Petrova Kaneva, PhD |
Contract №24-Д (2015) | Study of polymorphisms in COMT, MTHFR and MAO genes and their association in Bulgarian patients with Alzheimer's disease and Parkinson's disease | Kalina Yonkova Mihova, MSc |
Contract №23-Д (2015) | Confirmation of potentially pathogenic chromosomal microaberrations in patients with epilepsy and mental retardation detected by the method of comparative genomic hybridization | Valentina Liubenova Peycheva, PhD |
Contract №21 (2015) | Molecular genetic structure of polyresistant invasive and respiratory strains of Streptococcus pneumoniae isolated five years after the start of mass immunization of newborns in Bulgaria with pneumococcal vaccine | Prof. Lena Petrova Sechanova, MD |
Contract №20 (2015) | Application of next generation sequencing for detection of somatic mutations in gliomas and tumors of the gastrointestinal tract in a selected group of Bulgarian patients | Prof. Albena Kirilova Yordanova, PhD |
Contract №17-Д (2015) | Application of a next generation of sequencing to detect mutations leading to various manifestations of congenital anomalies of the kidneys and excretory system | Valentin Marinov Penchev, MSc |
Contract №16-Д (2015) | Analysis for the presence of germline mutations in a panel of 94 tumor-associated genes by next generation sequencing in Bulgarian patients with familial breast cancer | Assist. Daniela Rosenova Pencheva, PhD |
Contract №15-Д (2015) | Expression analysis of microRNAs as molecular markers for early diagnosis and prognosis in laryngeal carcinoma | Silva Garo Kyurkchiyan, PhD |
Contract №13-Д (2015) | Associative study of polymorphisms in the VEGF gene as prognostic factors in breast cancer | Mariela Borisova Vasileva-Slaveva, MD |
Contract №11 (2015) | Clonal origin of isolates of E. coli and K. pneumoniae producing carbapenemase- and / or broad-spectrum beta lactamases (ESBLs) and characterization of the localization of genes encoding these enzymes | Assoc. Prof. Rumyana Donkova Markovska-Davidkova, MD |
Contract №8-Д (2015) | Assessment of the relationship between markers of systemic inflammation (CRP, IL-6, IL-10, IL-33, CCL2 / MCP-1), vitamin D status and the course of the disease in patients with chronic spontaneous urticaria | Anna Valerieva Dimitrova, MD |
Contract №7-C (2015) | Analysis of a panel of genes associated with predisposition to the development of familial breast and ovarian cancer by next-generation sequencing | Acad. prof. Vanyo Ivanov Mitev, MD, D.Sc. |
Contract №5 (2015) | BPIFA1 (PLUNC) gene expression profile in patients with chronic rhinosinusitis and chronic purulent otitis | Prof. Diana Petrova Popova, MD, D.Sc. |
Contract №1 (2015) | Study of the association between polymorphic variants in diabetes - related genes and the risk of ischemic heart disease in Bulgarians | Prof. Kiril Liubenov Naydenov, PhD |
Contract №61 (2014) | Role of polymorphisms in the CD3Z gene in the etiology and pathogenesis of dermatomyositis in Bulgaria | Assoc. Prof. Liubomir Asenov Durmishev, MD |
Contract №58 (2014) | Mutation screening of Bulgarian patients with retinal degeneration | Prof. Silvia Zdravkova Cherninkova-Gopina, MD, D.Sc. |
Contract №57 (2014) | Clarification of the effects of structural aberrations affecting the LPP, CFHR1 and CFHR3 genes at the nucleotide sequence level | Assoc. Prof. Aneliya Hristova Bueva, MD |
Contract №56 (2014) | Analysis of the expression of microRNAs let-7a, miR-21 and miR-205 in Bulgarian patients with non-small cell lung carcinomas | Assoc. prof. Yanina Georgieva Slavova-Marinova, MD |
Contract №55 (2014) | Study of the role of HPV in the pathogenesis of esophageal carcinoma in Bulgarian patients | Assoc. Prof. Oleg Georgiev Cholakov, MD |
Contract №53 (2014) | Molecular-genetic analysis for carriers of mutations in the BRCA1 and BRCA2 genes in patients with ovarian cancer | Assoc. Prof. Rumen Georgiev Dimitrov, MD |
Contract №52 (2014) | Genomic screening in patients with idiopathic epilepsy and mental retardation | Prof. Ivan Olegovich Litvinenko, MD |
Contract №51 (2014) | Expression analysis of microribonucleic acids in peripheral blood and determination of their diagnostic and prognostic value in patients with systemic lupus erythematosus | Assoc. Prof. Simeon Valentinov Monov, MD |
Contract №46 (2014) | Methodology of obtaining and storing tumor tissues for the creation of a tissue bank from patients with carcinomas of the colon, stomach and thyroid gland | Prof. Georgi Todorov Todorov, MD |
Contract №42 (2014) | Validation of a next generation sequencing protocol with the IonTorrent PGM sequencer to detect mutations in the BRCA1 and BRCA2 genes. | Acad. prof. Vanyo Ivanov Mitev, MD, D.Sc. |
Contract №41 (2014) | Replication of the results of a pilot genomic exome study in an independent cohort of heroin-dependent individuals and controls | Prof. Radka Petrova Kaneva, PhD |
Contract №36 (2014) | Epidemiological typing, mechanisms of resistance to carbapenemase and / or broad-spectrum beta lactamases (ESBLs) - producing clinically significant and carrier members of the family Enterobacteriaceae in three University Hospitals in Sofia, Pleven and Varna | Assoc. Prof. Rumyana Donkova Markovska-Davidkova, MD |
Contract №28-Д (2014) | Preparation and storage of tissues for tissue bank expansion by patients with breast cancer | Mariela Borisova Vasileva-Slaveva, MD |
Contract №27 (2014) | Genomic associative studies as a modern approach to elucidating the genetic basis of arterial hypertension: a replicative study of positive signals for association in the Bulgarian population | Prof. Kiril Liubenov Naydenov, PhD |
Contract №24-Д (2014) | Mutation analysis of the LRRK2 gene in Bulgarian patients with Parkinson's disease. | Kalina Yonkova Mihova, MSc |
Contract №21-Д (2014) | Relationship of neurocognitive disorders in patients with BAD-type 1 and genetic polymorphisms in 5HTTLPR, FKPB5, 5HTR2A, NR3C1, MAOA- and VNTR genes | Mladen Germanov Penchev, MD |
Contract №20-Д (2014) | Role of mutations in mitochondrial DNA in the pathogenesis of nonsyndromic hearing loss associated with the use of aminoglycoside antibiotics | Iglika Petrova Stancheva, MD |
Contract №18-Д (2014) | Study of the role of the SALL1, EYA1 and SIX1 genes in the etiology of congenital abnormalities of the kidneys and urinary system. | Valentin Martinov Penchev, MSc |
Contract №17-Д (2014) | Analysis of the spectrum of somatic mutations in tumors of Bulgarian breast cancer patients by next generation sequencing | Assist. Daniela Rosenova Pencheva, PhD |
Contract №16-Д (2014) | Replicative study to establish a potential association between polymorphic variants in leading candidate genes from genomic-associative studies and ischemic heart disease in Bulgarian patients | Reni Stoyova Tzveova, PhD |
Contract №11-Д (2014) | Apoptosis and hypoxia in squamous cell carcinoma of the larynx - molecular and genetic factors | Assoc. Prof. Todor Miroslavov Popov, MD |
Contract №9 (2014) | Study of patients with established or suspected multiple endocrine neoplasia and evaluation of the relationship of the observed phenotype with variations in the MEN1 and MEN2 genes | Assoc. prof. Dimitar Dobrinov Charakchiev, MD |
Contract №70 (2013) | Expression of the fusion EML4-ALK oncogene in Bulgarian patients with non-small cell lung carcinomas | Assoc. prof. Yanina Georgieva Slavova-Marinova, MD |
Contract №61 (2013) | Study of the role of aberrations in the candidate genes SKAP2, SUMF1, CROCC and TNS1 for the pathology of congenital anomalies of the kidneys and urinary system. | Assoc. Prof. Aneliya Hristova Bueva, MD |
Contract №60 (2013) | Expression analysis of microribonucleic acids - 146 and - 155 in blood and synovial fluid in patients with rheumatoid arthritis and osteoarthritis and determination of their diagnostic and prognostic value | Prof. Zlatimir Gospodinov Kolarov, MD, D.Sc. |
Contract №56 (2013) | Molecular genetic analysis of genes with intermediate penetrance in BRCA negative patients with familial breast cancer | Prof. Svetlana Liubomirova Hristova, MD, D.Sc. |
Contract №33-Д (2013) | Relationship between neurocognitive disorders in patients with BAD-type 1 and genetic polymorphisms in the DISC1 gene | Mladen Germanov Penchev, MD |
Contract №32 (2013) | Study of the role of polymorphisms in RELN, COL1A1 and BMP2 genes in the pathogenesis of otosclerosis | Prof. Diana Petrova Popova, MD, D.Sc. |
Contract №30-Д (2013) | Possibilities of comparative genomic hybridization to reveal the etiology of congenital hypopituitarism associated with adenocorticotropic hormone deficiency, ocular, bone and urogenital abnormalities. | Ani Valentinova Aroyo, MD |
Contract №27-Д (2013) | Methodology of preparation and storage of tumor tissues for the establishment of prognostic and predictive factors in breast cancer | Mariela Borisova Vasileva-Slaveva, MD |
Contract №26 (2013) | Molecular defects in benign neonatal forms of epilepsy and clinical - electrophysiological syndromes | Prof. Albena Kirilova Yordanova, PhD |
Contract №26-Д (2013) | Genetic aspects of nonsyndromic hearing loss-connexin 26, 30 and 31 | Iglika Petrova Stancheva, MD |
Contract №25 (2013) | Investigation of genetic determinants of neurocognitive endophenotypes in addictions | Prof. Radka Petrova Kaneva, PhD |
Contract №25-Д (2013) | Screening for mutations in the LRRK2 gene in Bulgarian patients with Parkinson's disease | Kalina Yonkova Mihova, MSc |
Contract №19 (2013) | Clonal origin of multidrug-resistant invasive and respiratory strains of Streptococcus pneumoniae isolated before and after the introduction of mass immunization with pneumococcal conjugate vaccine (2006-2013). | Assoc. Prof. Rumyana Donkova Markovska-Davidkova, MD |
Contract №9 (2013) | Expression analysis of SOX2, SOX6, SOX8 and SOX9 genes and their applicability as prognostic markers in malignant glial tumors | Prof. Nikolay Stefanov Gabrovski, MD |
Contract №8 (2013) | Analysis of polymorphic variants in candidate genes associated with arterial hypertension in Bulgarian patients | Prof. Kiril Liubenov Naydenov, PhD |
Contract №7-Д (2013) | miRNAs expression profiling in plasma and urine from patients with prostate cancer | Assist. Darina Liudmilova Kachakova, PhD |
Contract №6-Д (2013) | Molecular and genetic factors of angiogenesis in squamous cell carcinomas of the larynx | Assoc. Prof. Todor Miroslavov Popov, MD |
Contract №3-Д (2013) | Expression analysis of molecular markers in circulating tumor cells (CTC) from peripheral blood in Bulgarian patients with metastatic breast cancer | Assist. Daniela Rosenova Pencheva, PhD |
Contract №2-Д (2013) | Associative study of polymorphic variants in leading candidates - genes from genomic, associative studies in patients with ischemic heart disease in the Bulgarian population | Reni Stoyova Tzveova, PhD |
Contract №59 (2012) | Introduction of mutation screening for transcription factors POU1F-1 (PIT-1), HESX1, SOX3 in patients with congenital hyposomatotropism | Prof. Iva Hristova Stoeva, MD |
Contract №55 (2012) | Study of the role of the RELN gene in the pathogenesis of otosclerosis | Prof. Diana Petrova Popova, MD, D.Sc. |
Contract №39 (2012) | Associative study of candidate genes CACNA1C and ANK3 from genomic associative studies in patients with bipolar affective disorder in the Bulgarian population | Prof. Vihra Krumova Milanova-Nesheva, MD, D.Sc. |
Contract №33 (2012) | Study of the molecular basis of hereditary spastic paraplegia with autosomal recessive type of inheritance through clinical and genetic study of patients of Roma ethnic origin | Prof. Albena Kirilova Yordanova, PhD |
Contract №29-Д (2012) | Introduction of SOX2 mutation analysis in Bulgarian patients with congenital hyposomatotropism and / or ocular abnormalities | Ani Valentinova Aroyo, MD |
Contract №21 (2012) | Genotype-phenotype correlations in neurodegenerative diseases with parkinsonism | Acad. Prof. Lachezar Traykov, MD, D.Sc. |
Contract №20-Д (2012) | Analysis of large genomic deletions, insertions and rearrangements in the BRCA1 and BRCA2 genes in Bulgarian patients with triple-negative breast cancer | Rumyana Ivanova Dodova, PhD |
Contract №19-Д (2012) | Expression profiling of miRNAs in prostate tissue and plasma in Bulgarian patients | Assist. Darina Liudmilova Kachakova, PhD |
Contract №18-Д (2012) | Influence of genetic factors on the therapy with indirect anticoagulants in Bulgarian patients with cardiovascular diseases | Reni Stoyova Tzveova, PhD |
Contract №17-Д (2012) | Expression analysis of CAIX, MMP-9 and TGF-β2 genes and their applicability as a prognostic marker in malignant glial tumors | Gergana Stefanova Stancheva, PhD |
Contract №15-Д (2012) | Molecular and genetic basis of angiogenesis in squamous cell carcinomas of the larynx | Assoc. Prof. Todor Miroslavov Popov, MD |
Contract №14-Д (2012) | Expression levels of microribonucleic acids in blood and synovial fluid as potential biomarkers for diagnosing, determining the severity and prognosis of rheumatoid arthritis | Ruska Petrova Shumnalieva, MD |
Contract №11-Д (2012) | Genetic aspects of nonsyndromic hearing loss - connexin 26 and 30 | Iglika Petrova Stancheva, MD |
Contract №59 (2011) | Detection of HFE gene mutations in patients with chronic liver disease with or without concomitant iron overload syndrome | Prof. Liudmila Mateva Vladimirova, MD, D.Sc. |
Contract №56 (2011) | Associative study of candidates and endophenotypes in bipolar affective disorder | Prof. Vihra Krumova Milanova-Nesheva, MD, D.Sc. |
Contract №51 (2011) | Investigation of the role of genomic changes, deletions and duplications, for the pathology of congenital anomalies of the kidneys and urinary tract (CAKUT) | Assoc. Prof. Aneliya Hristova Bueva, MD |
Contract №47 (2011) | Analysis of mutations in the BRCA1 gene in Bulgarian patients with triple-negative breast cancer | Prof. Svetlana Liubomirova Hristova, MD, D.Sc. |
Contract №30-Д (2011) | Molecular genetic analysis of the SLC2A1 gene and phenotype genotypic correlations in patients with early-onset childhood absence epilepsy | Daliya Metodieva Kancheva, PhD |
Contract №28-Д (2011) | Associative study of candidate genes for suicidal behavior in patients with different psychiatric diagnoses | Turan Selim Asan, MD |
Contract №26-Д (2011) | Role of promoter hypermethylation in laryngeal carcinogenesis | Stanislav Hristov Yordanov, MD |
Contract №25-Д (2011) | Genetic analysis for mutations in exon 11 of the BRCA2 gene in patients with familial breast cancer in the Bulgarian population | Rumyana Ivanova Dodova, PhD |
Contract №24-Д (2011) | Associative study of polymorphic variants located in chromosome locus 11p15 and evaluation of their significance for the development of prostate cancer | Assist. Darina Liudmilova Kachakova, PhD |
Contract №23-Д (2011) | Study of IDH1, IDH2 and TP53 genes and 1p / 19q chromosomal deletions in Bulgarian patients with malignant glial tumors | Gergana Stefanova Stancheva, PhD |
Contract №18 (2011) | Early cognitive impairment in patients with arterial hypertension | Prof. Kiril Liubenov Naydenov, PhD |
Contract №9-Д (2011) | Arterial hypertension. Early cognitive impairment | Teodora Ivanova Yaneva-Sirakova, MD |
Contract №1-Д (2011) | Primary neuroendocrine tumors of the lung - comparison between immunohistochemical expression markers and clinicopathological parameters | Assoc. Prof. Dora Marinova Marinova, MD |
Contract №28 (2010) | Investigation of promoter hypermethylation of biomakers in urine, associated with prostate cancer and evaluation of their diagnostic value in Bulgarian patients | Acad. prof. Chavdar Krumov Slavov, MD, D.Sc. |
Contract №27 (2010) | Study of the molecular basis of congenital anomalies of the kidneys and urinary tract (CAKUT) in Bulgaria. Role of PAX2 in the pathogenesis of CAKUT | Assoc. Prof. Aneliya Hristova Bueva, MD |
Contract №18-Д (2010) | Immunohistochemical and genetic expression markers in primary malignant epithelial lung tumors | Assoc. Prof. Dora Marinova Marinova, MD |
Contract №15 (2010) | Investigation of the connection between the polymorphisms in the MBL gene (mannosobinding lectin) and the occurrence of dermatomyositis in Bulgaria | Prof. Aleksey Slavkov Savov, PhD |
Contract №9-Д (2010) | Analysis of polymorphic variants in low penetrance genes associated with an increased risk of developing breast cancer | Rumyana Ivanova Dodova, PhD |
Contract №8-Д (2010) | Genetic markers with prognostic value in malignant glial tumors | Gergana Stefanova Stancheva, PhD |
Contract №59 (2009) | Squamous cell carcinoma of the larynx and hypopharynx. Genetic defects related to carcinogenesis and biological behavior of the tumor | Assoc. Prof. Ivan Yordanvo Chalakov, MD |
Contract №57 (2009) | Study of the relationship between polymorphisms in the interleukin-10 gene (IL-10) and the occurrence of dermatomyositis in Bulgaria | Assoc. Prof. Liubomir Asenov Durmishev, MD |
Contract №55 (2009) | Screening for unbalanced submicroscopic aberrations of subtelomeric and interstitial chromosomal regions in patients with idiopathic mental retardation | Prof. Aleksey Slavkov Savov, PhD |
Contract №54 (2009) | Analysis of large genomic deletions, insertions and rearrangements in the BRCA1 and BRCA2 genes in Bulgarian patients with hereditary breast cancer | Assoc. Prof. Atanaska Velichkova Mitkova, PhD |
Contract №53 (2009) | Study of genetic and epigenetic changes of FMR1 in Bulgarian patients with clinical phenotype of fragile X chromosome syndrome | Assoc. Prof. Radoslava Vasileva Vazharova, MD |
Contract №52 (2009) | Study of candidate genes in the region of attachment for familial partial epilepsy | Teodora Evgenieva Goranova, PhD |
Contract №51 (2009) | Analysis of polymorphic variants in candidate genes associated with prostate cancer | Prof. Radka Petrova Kaneva, PhD |
Contract №50 (2009) | Molecular diagnosis of deafness | Prof. Kuncho Velev Kunev, MD, D.Sc. |
Contract №44 (2009) | Determination of the mutation frequency in the MSH6 gene between patients with endometrial cancer whose biopsy materials show inactivating mutations in the KRAS gene | Darina Veselinova Konstantinova, PhD |
Contract №43 (2009) | Study of the role of hepatocyte nuclear factor 1-beta (HNF1β) in the development of congenital anomalies of the urinary system | Chief Assist. Olga Zhivanova Beltcheva, PhD |
Contract №10 (2009) | Familial association study of neurocognitive disorders and DISC1 gene in patients with bipolar disorder | Prof. Vihra Krumova Milanova-Nesheva, MD, D.Sc. |
Contract №9 (2009) | Phenotypic characteristics of an isolated population | Assist. Aneliya Tzolova Kancheva-Beleva, MD |
Contract №8И (2009) | Completion of units "Cell and tissue cultures" and "Microarray and laser microdissection" at the Center for Molecular Medicine, MU - Sofia | Acad. prof. Vanyo Ivanov Mitev, MD, D.Sc. |
Contract 4-С (2009) | Genetic, neuropsychological and vascular markers for early diagnosis of Alzheimer's disease and vascular dementia | Acad. Prof. Lachezar Traykov, MD, D.Sc. |
Contract №36 (2008) | Determination of the significance of the mutation analysis of the beta-catenin gene (CTNNB1) in patients with endometrial cancer | Acad. prof. Vanyo Ivanov Mitev, MD, D.Sc. |
Contract №26 (2008) | Study of the role of polymorphisms in tumor necrosis factor-alpha (TNF-α) for the pathology of dermatomyositis in Bulgaria | Assoc. Prof. Liubomir Asenov Durmishev, MD |
Contract №27-Д (2008) | Association of polymorphic variants in regulatory genes of androgen biosynthesis (CYP1B1, CYP19 and SRD5A2) with increased risk of developing prostate cancer in Bulgaria | Elenko Petkov Popov, MD |
Contract №24-Д (2008) | Screening for point mutations in the coagulation factor VIII gene in Bulgarian patients with hemophilia A | Ventzislav Rumenov Atanasov, MSc |
Contract №17 (2008) | Influence of genetic variants in the ABCA4 gene on the development of age-related macular degeneration (ARMD) and risk assessment of the disease in the Bulgarian population | Prof. Ivo Marinov Kremenski, MD, D.Sc. |
Contract №15 (2008) | Analysis of large genomic deletions, insertions and rearrangements in the MLH1 and MSH2 genes in Bulgarian patients with colorectal cancer | Prof. Radka Petrova Kaneva, PhD |
Contract №14 (2008) | Frequency and nature of mutations in the WT1 gene in patients with steroid-resistant nephrotic syndrome in Bulgaria | Chief Assist. Olga Zhivanova Beltcheva, PhD |
Contract №45 (2007) | Endophenotypic characteristics of patients with affective disorders | Prof. Vihra Krumova Milanova-Nesheva, MD, D.Sc. |
Contract №29 (2007) | Role of mutations in the podocin gene (NPHS2) for the pathology of steroid-resistant nephrotic syndrome and for the population risk of microalbuminuria in Bulgaria | Chief Assist. Olga Zhivanova Beltcheva, PhD |
Contract №28 (2007) | Investigation of the role of polymorphic variants of metabotropic glutamate receptor 1 for predisposition to affective disorders and drug dependence | Prof. Ivo Marinov Kremenski, MD |
Contract №27 (2007) | Study of the influence of mutations in the BRCA1 and BRCA2 genes on the development of breast cancer and prostate cancer | Assoc. Prof. Atanaska Velichkova Mitkova, PhD |
Contract №8-Д (2007) | Associative study on the role of allelic variants I157T and 1100delC in the CHEK2 gene in Bulgarian patients with colorectal and endometrial cancer | Darina Veselinova Konstantinova, PhD |
Contract №28 (2006) | Study of the role of polymorphisms in XRCC1 and XRCC3 genes for the development of early radiation reactions in cervical and endometrial carcinoma | Prof. Aleksey Slavkov Savov, PhD |
Contract №2 (2006) | Screening for molecular defects in the nipa1 gene in Bulgarian patients with hereditary spastic paraplegia | Neviana Ivanova Ivanova, PhD |
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