Bulgarian
Scientific Projects
Project number/Contract (year of funding) Project Name Head
Contract КП-06-ОПР 03/17 (2018) Investigation of the role of germinal and somatic genomic changes on the development of multiple primary tumors Acad. prof. Chavdar Krumov Slavov, MD, D.Sc.
Contract КП-06-Н23/9 (2018) Somatic changes in the most common benign (nodular goiter) and malignant (papillary thyroid carcinoma) thyroid tumors Chief Assit. Kalin Nikolaev Vidinov, MD
Contract № ДН13/12 (2017) Study of the regulation of neoangiogenesis in advanced laryngeal carcinoma Assoc. Prof. Todor Miroslavov Popov, MD
Contract № ДН03/14 (2016) MicroRNA profiling in adenocarcinomas and squamous cell carcinomas of the lung in Bulgarian patients Prof. Radka Petrova Kaneva, PhD
Contract № ДФНИ-Б02/6 (2014) Genetic study of endophenotypes in bipolar disorder Prof. Vihra Krumova Milanova-Nesheva, MD, D.Sc.
Contract № ДФНИ-Б02/3 (2014) Hereditary cerebellar ataxias - molecular epidemiology in the Bulgarian population and search for new forms Prof. Ivaylo Liudmilov Tarnev, MD, D.Sc.
Contract № ДФНИ-Б01/27 (2012) Genomic and exomatic associative research in heroin addiction in Bulgaria Prof. Ivo Marinov Kremenski, MD, D.Sc.
Contract № ДФНИ-Б01/28 (2012) Expression profiling of miRNAs in Bulgarian patients with prostate cancer and development of a panel of biomarkers for diagnosis and prognosis Prof. Radka Petrova Kaneva, PhD
Contract № ДМУ 03/73 (2011) Genomic analysis for mutations in patients with congenital abnormalities of the kidneys and urinary tract (CAKUT) Chief Assist. Olga Zhivanova Beltcheva, PhD
Contract № ДДВУ 02/35 (2010) Monitoring of circulating tumor cell (CTC) levels in patients with metastatic breast cancer - prognostic and predictive significance Assoc. Prof. Atanaska Velichkova Mitkova, PhD
Contract № ДДВУ 02/33 (2010) Analysis of the clinical and molecular characteristics of squamous cell carcinoma of the larynx and their applicability to determine the prognosis and efficacy of treatment Teodora Evgenieva Goranova, PhD
Contract № ДО12-7 (2010) Modern approach for diagnosis and determination of the frequency of genotypic-phenotypic correlations in patients with gestational diabetes mellitus in Bulgaria Assoc. Prof. Iliyana Borisova Atanasova, MD
Contract № ДТК02-49 (2009 ) Clinical and molecular markers with prognostic value for survival, quality of life and efficacy of treatment in malignant glial tumors Prof. Nikolay Stefanov Gabrovski, MD
Contract № ДТК 02/67 (2009) Modern approaches to discovering the genetic basis of epilepsy Prof. Albena Kirilova Yordanova, PhD
Contract № ДТК02-51 (2009) Complete genome screening for copy number variantions in mental retardation Assoc. Prof. Veneta Sashova Bozhinova-Chamova, MD
Contract № ДОО2_119 (2009) Study of genetic variants associated with increased risk and search for diagnostic and prognostic expression markers in prostate cancer Acad. prof. Chavdar Krumov Slavov, MD, D.Sc.
Contract Д002-310 (2008) Molecular pathways involved in breast cancer Prof. Elena Ivanova Georgieva, PhD
Contract ВУ-Л-317 (2007) Modern approach for diagnosis and study of hereditary mevromuscular diseases in Bulgaria - application of scientific knowledge for the benefit of the patient Prof. Ivaylo Liudmilov Tarnev, MD, D.Sc.
Project Number / Contract (year of funding) Project Name Head
FP6-ACC-SSA- 017147, (2005-2008), INCO MMCBG enhancing the capacity of biomedical рesearch in Bulgaria Prof. Ivo Marinov Kremenski, MD, D.Sc.
DRI15/ 2006 (2006-2008) Establishment of a sector for SNP genotyping and gene expression in MMC, MU-Sofia Acad. prof. Vladimir Atanasov Ovcharov, MD, D.Sc.
CVP01/0123 (2008-2010), Contract DO02-118 (2008) Increasing the research potential of MU-Sofia by establishing a collaborative, multidisciplinary Molecular Medicine Center as the main national infrastructure in the field of biobanking, functional genomics, proteomics and metabolomics Acad. prof. Vanyo Ivanov Mitev, MD, D.Sc.
URC_09_003/ 2009, Contract DUNK 01/2/2009 (2009-2019) The National University Complex for Biomedical and Translational Research Acad. prof. Vanyo Ivanov Mitev, MD, D.Sc.
8I/ 2009 (2009-2010) Increasing the capacity of scientific units in Cell and Tissue Cultivation, Microarray Analysis and Laser Microdissection of the Center for Molecular Medicine, MU-Sofia Acad. prof. Vanyo Ivanov Mitev, MD, D.Sc.
Д01-285/17.12.2019 “National University Complex for Biomedical and Translational Research, linked to participation in BBMRI-ERIC (NUCBTR and BBMRI.bg) Program” National Roadmap of Research Infrastructures 2017-2023”, MES Acad.Prof. V.Mitev
Д01-395/18.10.2020 “National University Complex for Biomedical and Translational Research, linked to participation in BBMRI-ERIC (NUCBTR and BBMRI.bg) Program” National Roadmap of Research Infrastructures 2020-2027”, MES Acad.Prof. V.Mitev
Project Number / Contract (year of funding) Project Name Head
Contract №Д-148 (2019) Molecular genetic analysis for mutations in the TERT, BRAF and NRAS genes in patients with papillary thyroid carcinoma Prof. Radka Petrova Kaneva, PhD
Contract №Д-144 (2019) TP53 мутационен статус при не-дребноклетъчен белодробен карцином Вероника Йорданова Петкова, MSc
Contract №Д-142 (2019) Study of rs2736340 polymorphisms in the FAM167A-BLK region as a factor in the development of dermatomyositis in adults Yoana Vladimirova Pozharashka, MD
Contract №Д-138 (2019) Investigation of genetic identity between laryngeal carcinoma and cervical metastases Venelin Marinov Marinov, MD
Contract №Д-135 (2019) Study of rare variants in genes encoding ion channels and their association in patients with bipolar disorder and schizophrenia Radosveta Dimitrova Bozhilova, MSc
Contract №Д-126 (2019) Genetic bases of cardiomyopathies in patients of Bulgarian origin Monika Ivanova Shumkova, MD
Contract №Д-116 (2019) Genetic analysis for mutations in the UMOD gene to detect autosomal dominant tubulo interstitial kidney disease Assoc. Prof. Mariya Simeonova Gaydarova, MD
Contract №Д-109 (2019) Establishment of a biobank for fecal microbiota for the purpose of safe and effective transplantation of fecal microbiota in Bulgaria Assoc. Prof. Ventzislav Nakov Nakov, MD
Contract №Д-104 (2019) Study of polymorphisms rs2279115, rs956572 in the Bcl2 gene as a factor in the development of dermatomyositis in adults Assoc. Prof. Liubomir Asenov Durmishev, MD
Contract №Д-73 (2019) Genetic factors causing changes in the normal function of the complement system and related renal impairment Chief Assist. Olga Zhivanova Beltcheva, PhD
Contract №Д-70 (2019) Analysis of somatic mutations in primary tumors with different localization in patients with multiple primary neoplasia Assoc. Prof. Atanaska Velichkova Mitkova, PhD
Contract №Д-232 (2018) Intestinal carriers of broad-spectrum beta-lactamase and / or carbapenemase - producing Enterbacteriaceace in hospitalized, outpatients and healthy people - children and adults Assoc. Prof. Rumyana Donkova Markovska-Davidkova, MD
Contract №Д-135 (2018) Frequency and spectrum of mutations in the PIK3CA gene in the Bulgarian population of breast cancer patients Slavyana Slavcheva Usheva, MD
Contract №Д-134 (2018) Expression analysis of key genes associated with immune response avoidance in lung cancer Veronika Yordanova Petkova, MSc
Contract №Д-131 (2018) Study of rare variants in SHANK1 and SHANK2 genes and their association with bipolar disorder and schizophrenia in Bulgarian patients Radosveta Dimitrova Bozhilova, MSc
Contract №Д-123 (2018) Genetic expression analysis of selected genes and comparison with serum levels of their products in Bulgarian patients with benign thyroid nodules and papillary thyroid carcinoma Inna Dimitrova Dimitrova, MD
Contract №Д-115 (2018) Analysis for promoter hypermethylation of tumor suppressor genes in ovarian carcinoma Assoc. Prof. Rumen Georgiev Dimitrov, MD
Contract №Д-109 (2018) Identification of gene mutations leading to retinal degeneration in Bulgarian patients by next generation sequencing of target genes Prof. Silvia Zdravkova Cherninkova-Gopina, MD, D.Sc.
Contract №Д-73 (2018) Genetic factors and clinical characteristics of vascular complications in Bulgarian patients with type 2 diabetes mellitus Prof. Radka Petrova Kaneva, PhD
Contract №Д-72 (2018) Promoter hypermethylation of tumor suppressor genes in patients with breast cancer Prof. Svetlana Liubomirova Hristova, MD, D.Sc.
Contract №Д-71 (2018) Study of the role of genes associated with familial cancer syndromes on the development of multiple primary tumors Assoc. Prof. Atanaska Velichkova Mitkova, PhD
Contract №Д-62 (2018) miRNA predictive profile for risk assessment of cardiovascular complications in type 2 diabetes mellitus Prof. Ivanka Istalianova Dimova, MD
Contract №Д-59 (2018) Next generation sequencing of target genes for identification of genetic mutations in Bulgarian patients with familial forms of hematuria Chief Assist. Olga Zhivanova Beltcheva, PhD
Contract №Д-54 (2018) Study of the mechanisms of chromosomal and plasmid quinolone resistance in third generation cephalosporins and / or carbapenem-resistant clinically significant isolates of Klebsiella spp at Sveta Marina University Hospital Varna Assoc. Prof. Rumyana Donkova Markovska-Davidkova, MD
Contract №Д-123 (2017) Study of methotrexate drug-related genetic polymorphisms in patients with adolescent idiopathic arthritis Assoc. Prof. Stefan Nedev Stefanov, MD
Contract №Д-115 (2017) Study of the polymorphisms rs1799782 and rs25487 in the XRCC1 gene as factors for the development of dermatomyositis in adults Assoc. Prof. Liubomir Asenov Durmishev, MD
Contract №Д-77 (2017) Study of copy number variants in patients with Parkinson's disease Prof. Albena Kirilova Yordanova, PhD
Contract №Д-75 (2017) Clarification of the role of selected polymorphic variants in genes associated with blood pressure values in relation to the risk of developing ischemic heart disease Prof. Radka Petrova Kaneva, PhD
Contract №Д-70 (2017) Influence of the rs266729 promoter polymorphism on the transcriptional regulation of the adiponectin gene (ADIPOQ) in normal pregnancy and gestational diabetes Chief Assist. Olga Zhivanova Beltcheva, PhD
Contract №Д-69 (2017) Post-vaccine effect of 10-valent pneumococcal conjugate vaccine (PHiD-PCV10) on the etiology of acute otitis media (AOM) and carrier of otopathogenic bacteria in children with AOM in 2015-2016 Prof. Lena Petrova Sechanova, MD
Contract №Д-62 (2017) Next generation sequencing of patients with hereditary neurosensory hearing loss to clarify the genetic cause of hearing loss Prof. Diana Petrova Popova, MD, D.Sc.
Contract №Д-59 (2017) Study of the main mechanisms of resistance to beta-lactams and quinolones in third-generation cephalosporin-resistant and / or carbapenems clinically significant isolates of Enterobacter spp at the University Hospital "St. Marina" Varna Assoc. Prof. Rumyana Donkova Markovska-Davidkova, MD
Contract №Д-144 (2017) Expression of androgen receptor in association with other prognostic and predictive factors in Bulgarian breast cancer patients Slavyana Slavcheva Usheva, MD
Contract №Д-138 (2017) Molecular profiling of the main histological types of lung carcinomas Veronika Yordanova Petkova, MSc
Contract №Д-137 (2017) Investigation of the role of hypoxic microRNAs in laryngeal carcinoma Silva Garo Kyurkchiyan, PhD
Contract №Д-132 (2017) Evaluation of the importance of a panel of somatic mutations as prognostic factors in gastric cancer Angel Nikolaev Arabadzhiev, MD
Contract №97 (2016) Expansion of the biobank from patients with ovarian cancer and optimization of the conditions for storage of biological materials Assoc. Prof. Rumen Georgiev Dimitrov, MD
Contract №96 (2016) Tissue storage to further expand tissue, plasma and DNA bank of breast cancer patients Assoc. Prof. Teofil Angelov Sedloev, MD
Contract №90 (2016) Plasma miRNA expression analysis in patients with non-small cell lung carcinomas and obstructive pulmonary disease Assoc. prof. Yanina Georgieva Slavova-Marinova, MD
Contract №83 (2016) Non-classical forms of 21-hydroxylase deficiency: clinical and molecular genetic diagnosis Prof. Iva Hristova Stoeva, MD
Contract №81 (2016) Epigenetic biomarkers in Bulgarian patients with esophageal tumors Assoc. Prof. Oleg Georgiev Cholakov, MD
Contract №76 (2016) Expression analysis of plasma microribonucleic acids in patients with rheumatoid arthritis and determination of their diagnostic and prognostic value Prof. Zlatimir Gospodinov Kolarov, MD, D.Sc.
Contract №75 (2016) Determination of diagnostic and prognostic value of microribonucleic acids in plasma in patients with systemic lupus erythematosus Assoc. Prof. Simeon Valentinov Monov, MD
Contract №67 (2016) Study of the relationship between IL-17 polymorphisms rs2275913 and serum IL-17 levels - factors for the development of dermatomyositis in adults Assoc. Prof. Liubomir Asenov Durmishev, MD
Contract №63 (2016) Study of the role of pharmacogenetic factors in refining drug therapy with tacrolimus in patients with kidney transplantation in Bulgaria Prof. Emil Paskalev Dimitrov, MD, D.Sc.
Contract №35 (2016) Confirmatory analysis of potentially pathogenic variants in Parkinson's disease-related genes found through next generation sequencing Prof. Albena Kirilova Yordanova, PhD
Contract №30 (2016) Genetic profiling of laryngeal carcinoma by next generation sequencing Prof. Diana Petrova Popova, MD, D.Sc.
Contract №29 (2016) Molecular markers of diagnostic and prognostic value in the treatment of solid tumors in childhood Prof. Radka Petrova Kaneva, PhD
Contract №27 (2016) Analysis of somatic mutations in Bulgarian patients with colorectal and gastric carcinomas by next generation sequencing of a panel of tumor-associated genes Prof. Georgi Todorov Todorov, MD
Contract №26 (2016) Associative analysis of polymorphic markers in or near selected candidate genes associated with predisposition to arterial hypertension in Bulgarians Prof. Kiril Liubenov Naydenov, PhD
Contract №24 (2016) Analysis of somatic mutations in the main histological types of lung carcinomas: PC, AK, NET (CT, DKBD and ECNE) in a group of Bulgarian patients by next generation sequencing of a panel of tumor-associated genes Assoc. Prof. Atanaska Velichkova Mitkova, PhD
Contract №12-Д (2016) Expression analysis of an expanded panel of selected hypoxic microRNAs in patients diagnosed with laryngeal cancer in tissue and plasma samples Silva Garo Kyurkchiyan, PhD
Contract №11-Д (2016) Expression analysis of Toll-like receptor 2 (TLR2), Toll-like receptor 4 (TLR4) and Toll-like receptor 7 (TLR7) in patients with chronic purulent otitis and chronic rhinosinusitis Stoyan Ivanov Dimitrov, MD
Contract №8-Д (2016) Next generation sequencing by synthesis in selected patients with different characteristics of congenital anomalies of the kidneys and urinary tract (CAKUT) Valentin Martinov Penchev, MSc
Contract №6-Д (2016) Mutations in the gene encoding hTPO among clinically selected Bulgarian patients with primary congenital hypothyroidism Boris Georgiev Stoilov
Contract №5-Д (2016) Quantitative real-time PCR of chromosomal microaberrations detected in patients with complex epileptic syndromes using microarray technology Valentina Liubenova Peycheva, PhD
Contract №68 (2015) Analysis of polymorphic variants in candidate genes associated with response to methotrexate therapy in children with juvenile idiopathic arthritis Assoc. Prof. Stefan Nedev Stefanov, MD
Contract №66 (2015) Genetic changes in primary glioblastomas and their relationship with the prognosis in Bulgarian patients Prof. Nikolay Stefanov Gabrovski, MD
Contract №62 (2015) Expression analysis of serum microribonucleic acids and determination of their diagnostic and prognostic value in patients with progressive systemic sclerosis Prof. Zlatimir Gospodinov Kolarov, MD, D.Sc.
Contract №61 (2015) Next diagnostic and prognostic biomarkers in rheumatoid arthritis Assoc. Prof. Simeon Valentinov Monov, MD
Contract №55 (2015) Role of promoter hypermethylation in the CD3Z gene for the etiology and pathogenesis of dermatomyositis Assoc. Prof. Liubomir Asenov Durmishev, MD
Contract №50 (2015) Next generation sequencing of target genes for retinal degeneration in Bulgarian patients Prof. Silvia Zdravkova Cherninkova-Gopina, MD, D.Sc.
Contract №24 (2015) Development of a non-invasive method for assessment of the implantation potential of human embryos based on the expression of miRNAs in the culture medium Prof. Radka Petrova Kaneva, PhD
Contract №24-Д (2015) Study of polymorphisms in COMT, MTHFR and MAO genes and their association in Bulgarian patients with Alzheimer's disease and Parkinson's disease Kalina Yonkova Mihova, MSc
Contract №23-Д (2015) Confirmation of potentially pathogenic chromosomal microaberrations in patients with epilepsy and mental retardation detected by the method of comparative genomic hybridization Valentina Liubenova Peycheva, PhD
Contract №21 (2015) Molecular genetic structure of polyresistant invasive and respiratory strains of Streptococcus pneumoniae isolated five years after the start of mass immunization of newborns in Bulgaria with pneumococcal vaccine Prof. Lena Petrova Sechanova, MD
Contract №20 (2015) Application of next generation sequencing for detection of somatic mutations in gliomas and tumors of the gastrointestinal tract in a selected group of Bulgarian patients Prof. Albena Kirilova Yordanova, PhD
Contract №17-Д (2015) Application of a next generation of sequencing to detect mutations leading to various manifestations of congenital anomalies of the kidneys and excretory system Valentin Marinov Penchev, MSc
Contract №16-Д (2015) Analysis for the presence of germline mutations in a panel of 94 tumor-associated genes by next generation sequencing in Bulgarian patients with familial breast cancer Assist. Daniela Rosenova Pencheva, PhD
Contract №15-Д (2015) Expression analysis of microRNAs as molecular markers for early diagnosis and prognosis in laryngeal carcinoma Silva Garo Kyurkchiyan, PhD
Contract №13-Д (2015) Associative study of polymorphisms in the VEGF gene as prognostic factors in breast cancer Mariela Borisova Vasileva-Slaveva, MD
Contract №11 (2015) Clonal origin of isolates of E. coli and K. pneumoniae producing carbapenemase- and / or broad-spectrum beta lactamases (ESBLs) and characterization of the localization of genes encoding these enzymes Assoc. Prof. Rumyana Donkova Markovska-Davidkova, MD
Contract №8-Д (2015) Assessment of the relationship between markers of systemic inflammation (CRP, IL-6, IL-10, IL-33, CCL2 / MCP-1), vitamin D status and the course of the disease in patients with chronic spontaneous urticaria Anna Valerieva Dimitrova, MD
Contract №7-C (2015) Analysis of a panel of genes associated with predisposition to the development of familial breast and ovarian cancer by next-generation sequencing Acad. prof. Vanyo Ivanov Mitev, MD, D.Sc.
Contract №5 (2015) BPIFA1 (PLUNC) gene expression profile in patients with chronic rhinosinusitis and chronic purulent otitis Prof. Diana Petrova Popova, MD, D.Sc.
Contract №1 (2015) Study of the association between polymorphic variants in diabetes - related genes and the risk of ischemic heart disease in Bulgarians Prof. Kiril Liubenov Naydenov, PhD
Contract №61 (2014) Role of polymorphisms in the CD3Z gene in the etiology and pathogenesis of dermatomyositis in Bulgaria Assoc. Prof. Liubomir Asenov Durmishev, MD
Contract №58 (2014) Mutation screening of Bulgarian patients with retinal degeneration Prof. Silvia Zdravkova Cherninkova-Gopina, MD, D.Sc.
Contract №57 (2014) Clarification of the effects of structural aberrations affecting the LPP, CFHR1 and CFHR3 genes at the nucleotide sequence level Assoc. Prof. Aneliya Hristova Bueva, MD
Contract №56 (2014) Analysis of the expression of microRNAs let-7a, miR-21 and miR-205 in Bulgarian patients with non-small cell lung carcinomas Assoc. prof. Yanina Georgieva Slavova-Marinova, MD
Contract №55 (2014) Study of the role of HPV in the pathogenesis of esophageal carcinoma in Bulgarian patients Assoc. Prof. Oleg Georgiev Cholakov, MD
Contract №53 (2014) Molecular-genetic analysis for carriers of mutations in the BRCA1 and BRCA2 genes in patients with ovarian cancer Assoc. Prof. Rumen Georgiev Dimitrov, MD
Contract №52 (2014) Genomic screening in patients with idiopathic epilepsy and mental retardation Prof. Ivan Olegovich Litvinenko, MD
Contract №51 (2014) Expression analysis of microribonucleic acids in peripheral blood and determination of their diagnostic and prognostic value in patients with systemic lupus erythematosus Assoc. Prof. Simeon Valentinov Monov, MD
Contract №46 (2014) Methodology of obtaining and storing tumor tissues for the creation of a tissue bank from patients with carcinomas of the colon, stomach and thyroid gland Prof. Georgi Todorov Todorov, MD
Contract №42 (2014) Validation of a next generation sequencing protocol with the IonTorrent PGM sequencer to detect mutations in the BRCA1 and BRCA2 genes. Acad. prof. Vanyo Ivanov Mitev, MD, D.Sc.
Contract №41 (2014) Replication of the results of a pilot genomic exome study in an independent cohort of heroin-dependent individuals and controls Prof. Radka Petrova Kaneva, PhD
Contract №36 (2014) Epidemiological typing, mechanisms of resistance to carbapenemase and / or broad-spectrum beta lactamases (ESBLs) - producing clinically significant and carrier members of the family Enterobacteriaceae in three University Hospitals in Sofia, Pleven and Varna Assoc. Prof. Rumyana Donkova Markovska-Davidkova, MD
Contract №28-Д (2014) Preparation and storage of tissues for tissue bank expansion by patients with breast cancer Mariela Borisova Vasileva-Slaveva, MD
Contract №27 (2014) Genomic associative studies as a modern approach to elucidating the genetic basis of arterial hypertension: a replicative study of positive signals for association in the Bulgarian population Prof. Kiril Liubenov Naydenov, PhD
Contract №24-Д (2014) Mutation analysis of the LRRK2 gene in Bulgarian patients with Parkinson's disease. Kalina Yonkova Mihova, MSc
Contract №21-Д (2014) Relationship of neurocognitive disorders in patients with BAD-type 1 and genetic polymorphisms in 5HTTLPR, FKPB5, 5HTR2A, NR3C1, MAOA- and VNTR genes Mladen Germanov Penchev, MD
Contract №20-Д (2014) Role of mutations in mitochondrial DNA in the pathogenesis of nonsyndromic hearing loss associated with the use of aminoglycoside antibiotics Iglika Petrova Stancheva, MD
Contract №18-Д (2014) Study of the role of the SALL1, EYA1 and SIX1 genes in the etiology of congenital abnormalities of the kidneys and urinary system. Valentin Martinov Penchev, MSc
Contract №17-Д (2014) Analysis of the spectrum of somatic mutations in tumors of Bulgarian breast cancer patients by next generation sequencing Assist. Daniela Rosenova Pencheva, PhD
Contract №16-Д (2014) Replicative study to establish a potential association between polymorphic variants in leading candidate genes from genomic-associative studies and ischemic heart disease in Bulgarian patients Reni Stoyova Tzveova, PhD
Contract №11-Д (2014) Apoptosis and hypoxia in squamous cell carcinoma of the larynx - molecular and genetic factors Assoc. Prof. Todor Miroslavov Popov, MD
Contract №9 (2014) Study of patients with established or suspected multiple endocrine neoplasia and evaluation of the relationship of the observed phenotype with variations in the MEN1 and MEN2 genes Assoc. prof. Dimitar Dobrinov Charakchiev, MD
Contract №70 (2013) Expression of the fusion EML4-ALK oncogene in Bulgarian patients with non-small cell lung carcinomas Assoc. prof. Yanina Georgieva Slavova-Marinova, MD
Contract №61 (2013) Study of the role of aberrations in the candidate genes SKAP2, SUMF1, CROCC and TNS1 for the pathology of congenital anomalies of the kidneys and urinary system. Assoc. Prof. Aneliya Hristova Bueva, MD
Contract №60 (2013) Expression analysis of microribonucleic acids - 146 and - 155 in blood and synovial fluid in patients with rheumatoid arthritis and osteoarthritis and determination of their diagnostic and prognostic value Prof. Zlatimir Gospodinov Kolarov, MD, D.Sc.
Contract №56 (2013) Molecular genetic analysis of genes with intermediate penetrance in BRCA negative patients with familial breast cancer Prof. Svetlana Liubomirova Hristova, MD, D.Sc.
Contract №33-Д (2013) Relationship between neurocognitive disorders in patients with BAD-type 1 and genetic polymorphisms in the DISC1 gene Mladen Germanov Penchev, MD
Contract №32 (2013) Study of the role of polymorphisms in RELN, COL1A1 and BMP2 genes in the pathogenesis of otosclerosis Prof. Diana Petrova Popova, MD, D.Sc.
Contract №30-Д (2013) Possibilities of comparative genomic hybridization to reveal the etiology of congenital hypopituitarism associated with adenocorticotropic hormone deficiency, ocular, bone and urogenital abnormalities. Ani Valentinova Aroyo, MD
Contract №27-Д (2013) Methodology of preparation and storage of tumor tissues for the establishment of prognostic and predictive factors in breast cancer Mariela Borisova Vasileva-Slaveva, MD
Contract №26 (2013) Molecular defects in benign neonatal forms of epilepsy and clinical - electrophysiological syndromes Prof. Albena Kirilova Yordanova, PhD
Contract №26-Д (2013) Genetic aspects of nonsyndromic hearing loss-connexin 26, 30 and 31 Iglika Petrova Stancheva, MD
Contract №25 (2013) Investigation of genetic determinants of neurocognitive endophenotypes in addictions Prof. Radka Petrova Kaneva, PhD
Contract №25-Д (2013) Screening for mutations in the LRRK2 gene in Bulgarian patients with Parkinson's disease Kalina Yonkova Mihova, MSc
Contract №19 (2013) Clonal origin of multidrug-resistant invasive and respiratory strains of Streptococcus pneumoniae isolated before and after the introduction of mass immunization with pneumococcal conjugate vaccine (2006-2013). Assoc. Prof. Rumyana Donkova Markovska-Davidkova, MD
Contract №9 (2013) Expression analysis of SOX2, SOX6, SOX8 and SOX9 genes and their applicability as prognostic markers in malignant glial tumors Prof. Nikolay Stefanov Gabrovski, MD
Contract №8 (2013) Analysis of polymorphic variants in candidate genes associated with arterial hypertension in Bulgarian patients Prof. Kiril Liubenov Naydenov, PhD
Contract №7-Д (2013) miRNAs expression profiling in plasma and urine from patients with prostate cancer Assist. Darina Liudmilova Kachakova, PhD
Contract №6-Д (2013) Molecular and genetic factors of angiogenesis in squamous cell carcinomas of the larynx Assoc. Prof. Todor Miroslavov Popov, MD
Contract №3-Д (2013) Expression analysis of molecular markers in circulating tumor cells (CTC) from peripheral blood in Bulgarian patients with metastatic breast cancer Assist. Daniela Rosenova Pencheva, PhD
Contract №2-Д (2013) Associative study of polymorphic variants in leading candidates - genes from genomic, associative studies in patients with ischemic heart disease in the Bulgarian population Reni Stoyova Tzveova, PhD
Contract №59 (2012) Introduction of mutation screening for transcription factors POU1F-1 (PIT-1), HESX1, SOX3 in patients with congenital hyposomatotropism Prof. Iva Hristova Stoeva, MD
Contract №55 (2012) Study of the role of the RELN gene in the pathogenesis of otosclerosis Prof. Diana Petrova Popova, MD, D.Sc.
Contract №39 (2012) Associative study of candidate genes CACNA1C and ANK3 from genomic associative studies in patients with bipolar affective disorder in the Bulgarian population Prof. Vihra Krumova Milanova-Nesheva, MD, D.Sc.
Contract №33 (2012) Study of the molecular basis of hereditary spastic paraplegia with autosomal recessive type of inheritance through clinical and genetic study of patients of Roma ethnic origin Prof. Albena Kirilova Yordanova, PhD
Contract №29-Д (2012) Introduction of SOX2 mutation analysis in Bulgarian patients with congenital hyposomatotropism and / or ocular abnormalities Ani Valentinova Aroyo, MD
Contract №21 (2012) Genotype-phenotype correlations in neurodegenerative diseases with parkinsonism Acad. Prof. Lachezar Traykov, MD, D.Sc.
Contract №20-Д (2012) Analysis of large genomic deletions, insertions and rearrangements in the BRCA1 and BRCA2 genes in Bulgarian patients with triple-negative breast cancer Rumyana Ivanova Dodova, PhD
Contract №19-Д (2012) Expression profiling of miRNAs in prostate tissue and plasma in Bulgarian patients Assist. Darina Liudmilova Kachakova, PhD
Contract №18-Д (2012) Influence of genetic factors on the therapy with indirect anticoagulants in Bulgarian patients with cardiovascular diseases Reni Stoyova Tzveova, PhD
Contract №17-Д (2012) Expression analysis of CAIX, MMP-9 and TGF-β2 genes and their applicability as a prognostic marker in malignant glial tumors Gergana Stefanova Stancheva, PhD
Contract №15-Д (2012) Molecular and genetic basis of angiogenesis in squamous cell carcinomas of the larynx Assoc. Prof. Todor Miroslavov Popov, MD
Contract №14-Д (2012) Expression levels of microribonucleic acids in blood and synovial fluid as potential biomarkers for diagnosing, determining the severity and prognosis of rheumatoid arthritis Ruska Petrova Shumnalieva, MD
Contract №11-Д (2012) Genetic aspects of nonsyndromic hearing loss - connexin 26 and 30 Iglika Petrova Stancheva, MD
Contract №59 (2011) Detection of HFE gene mutations in patients with chronic liver disease with or without concomitant iron overload syndrome Prof. Liudmila Mateva Vladimirova, MD, D.Sc.
Contract №56 (2011) Associative study of candidates and endophenotypes in bipolar affective disorder Prof. Vihra Krumova Milanova-Nesheva, MD, D.Sc.
Contract №51 (2011) Investigation of the role of genomic changes, deletions and duplications, for the pathology of congenital anomalies of the kidneys and urinary tract (CAKUT) Assoc. Prof. Aneliya Hristova Bueva, MD
Contract №47 (2011) Analysis of mutations in the BRCA1 gene in Bulgarian patients with triple-negative breast cancer Prof. Svetlana Liubomirova Hristova, MD, D.Sc.
Contract №30-Д (2011) Molecular genetic analysis of the SLC2A1 gene and phenotype genotypic correlations in patients with early-onset childhood absence epilepsy Daliya Metodieva Kancheva, PhD
Contract №28-Д (2011) Associative study of candidate genes for suicidal behavior in patients with different psychiatric diagnoses Turan Selim Asan, MD
Contract №26-Д (2011) Role of promoter hypermethylation in laryngeal carcinogenesis Stanislav Hristov Yordanov, MD
Contract №25-Д (2011) Genetic analysis for mutations in exon 11 of the BRCA2 gene in patients with familial breast cancer in the Bulgarian population Rumyana Ivanova Dodova, PhD
Contract №24-Д (2011) Associative study of polymorphic variants located in chromosome locus 11p15 and evaluation of their significance for the development of prostate cancer Assist. Darina Liudmilova Kachakova, PhD
Contract №23-Д (2011) Study of IDH1, IDH2 and TP53 genes and 1p / 19q chromosomal deletions in Bulgarian patients with malignant glial tumors Gergana Stefanova Stancheva, PhD
Contract №18 (2011) Early cognitive impairment in patients with arterial hypertension Prof. Kiril Liubenov Naydenov, PhD
Contract №9-Д (2011) Arterial hypertension. Early cognitive impairment Teodora Ivanova Yaneva-Sirakova, MD
Contract №1-Д (2011) Primary neuroendocrine tumors of the lung - comparison between immunohistochemical expression markers and clinicopathological parameters Assoc. Prof. Dora Marinova Marinova, MD
Contract №28 (2010) Investigation of promoter hypermethylation of biomakers in urine, associated with prostate cancer and evaluation of their diagnostic value in Bulgarian patients Acad. prof. Chavdar Krumov Slavov, MD, D.Sc.
Contract №27 (2010) Study of the molecular basis of congenital anomalies of the kidneys and urinary tract (CAKUT) in Bulgaria. Role of PAX2 in the pathogenesis of CAKUT Assoc. Prof. Aneliya Hristova Bueva, MD
Contract №18-Д (2010) Immunohistochemical and genetic expression markers in primary malignant epithelial lung tumors Assoc. Prof. Dora Marinova Marinova, MD
Contract №15 (2010) Investigation of the connection between the polymorphisms in the MBL gene (mannosobinding lectin) and the occurrence of dermatomyositis in Bulgaria Prof. Aleksey Slavkov Savov, PhD
Contract №9-Д (2010) Analysis of polymorphic variants in low penetrance genes associated with an increased risk of developing breast cancer Rumyana Ivanova Dodova, PhD
Contract №8-Д (2010) Genetic markers with prognostic value in malignant glial tumors Gergana Stefanova Stancheva, PhD
Contract №59 (2009) Squamous cell carcinoma of the larynx and hypopharynx. Genetic defects related to carcinogenesis and biological behavior of the tumor Assoc. Prof. Ivan Yordanvo Chalakov, MD
Contract №57 (2009) Study of the relationship between polymorphisms in the interleukin-10 gene (IL-10) and the occurrence of dermatomyositis in Bulgaria Assoc. Prof. Liubomir Asenov Durmishev, MD
Contract №55 (2009) Screening for unbalanced submicroscopic aberrations of subtelomeric and interstitial chromosomal regions in patients with idiopathic mental retardation Prof. Aleksey Slavkov Savov, PhD
Contract №54 (2009) Analysis of large genomic deletions, insertions and rearrangements in the BRCA1 and BRCA2 genes in Bulgarian patients with hereditary breast cancer Assoc. Prof. Atanaska Velichkova Mitkova, PhD
Contract №53 (2009) Study of genetic and epigenetic changes of FMR1 in Bulgarian patients with clinical phenotype of fragile X chromosome syndrome Assoc. Prof. Radoslava Vasileva Vazharova, MD
Contract №52 (2009) Study of candidate genes in the region of attachment for familial partial epilepsy Teodora Evgenieva Goranova, PhD
Contract №51 (2009) Analysis of polymorphic variants in candidate genes associated with prostate cancer Prof. Radka Petrova Kaneva, PhD
Contract №50 (2009) Molecular diagnosis of deafness Prof. Kuncho Velev Kunev, MD, D.Sc.
Contract №44 (2009) Determination of the mutation frequency in the MSH6 gene between patients with endometrial cancer whose biopsy materials show inactivating mutations in the KRAS gene Darina Veselinova Konstantinova, PhD
Contract №43 (2009) Study of the role of hepatocyte nuclear factor 1-beta (HNF1β) in the development of congenital anomalies of the urinary system Chief Assist. Olga Zhivanova Beltcheva, PhD
Contract №10 (2009) Familial association study of neurocognitive disorders and DISC1 gene in patients with bipolar disorder Prof. Vihra Krumova Milanova-Nesheva, MD, D.Sc.
Contract №9 (2009) Phenotypic characteristics of an isolated population Assist. Aneliya Tzolova Kancheva-Beleva, MD
Contract №8И (2009) Completion of units "Cell and tissue cultures" and "Microarray and laser microdissection" at the Center for Molecular Medicine, MU - Sofia Acad. prof. Vanyo Ivanov Mitev, MD, D.Sc.
Contract 4-С (2009) Genetic, neuropsychological and vascular markers for early diagnosis of Alzheimer's disease and vascular dementia Acad. Prof. Lachezar Traykov, MD, D.Sc.
Contract №36 (2008) Determination of the significance of the mutation analysis of the beta-catenin gene (CTNNB1) in patients with endometrial cancer Acad. prof. Vanyo Ivanov Mitev, MD, D.Sc.
Contract №26 (2008) Study of the role of polymorphisms in tumor necrosis factor-alpha (TNF-α) for the pathology of dermatomyositis in Bulgaria Assoc. Prof. Liubomir Asenov Durmishev, MD
Contract №27-Д (2008) Association of polymorphic variants in regulatory genes of androgen biosynthesis (CYP1B1, CYP19 and SRD5A2) with increased risk of developing prostate cancer in Bulgaria Elenko Petkov Popov, MD
Contract №24-Д (2008) Screening for point mutations in the coagulation factor VIII gene in Bulgarian patients with hemophilia A Ventzislav Rumenov Atanasov, MSc
Contract №17 (2008) Influence of genetic variants in the ABCA4 gene on the development of age-related macular degeneration (ARMD) and risk assessment of the disease in the Bulgarian population Prof. Ivo Marinov Kremenski, MD, D.Sc.
Contract №15 (2008) Analysis of large genomic deletions, insertions and rearrangements in the MLH1 and MSH2 genes in Bulgarian patients with colorectal cancer Prof. Radka Petrova Kaneva, PhD
Contract №14 (2008) Frequency and nature of mutations in the WT1 gene in patients with steroid-resistant nephrotic syndrome in Bulgaria Chief Assist. Olga Zhivanova Beltcheva, PhD
Contract №45 (2007) Endophenotypic characteristics of patients with affective disorders Prof. Vihra Krumova Milanova-Nesheva, MD, D.Sc.
Contract №29 (2007) Role of mutations in the podocin gene (NPHS2) for the pathology of steroid-resistant nephrotic syndrome and for the population risk of microalbuminuria in Bulgaria Chief Assist. Olga Zhivanova Beltcheva, PhD
Contract №28 (2007) Investigation of the role of polymorphic variants of metabotropic glutamate receptor 1 for predisposition to affective disorders and drug dependence Prof. Ivo Marinov Kremenski, MD
Contract №27 (2007) Study of the influence of mutations in the BRCA1 and BRCA2 genes on the development of breast cancer and prostate cancer Assoc. Prof. Atanaska Velichkova Mitkova, PhD
Contract №8-Д (2007) Associative study on the role of allelic variants I157T and 1100delC in the CHEK2 gene in Bulgarian patients with colorectal and endometrial cancer Darina Veselinova Konstantinova, PhD
Contract №28 (2006) Study of the role of polymorphisms in XRCC1 and XRCC3 genes for the development of early radiation reactions in cervical and endometrial carcinoma Prof. Aleksey Slavkov Savov, PhD
Contract №2 (2006) Screening for molecular defects in the nipa1 gene in Bulgarian patients with hereditary spastic paraplegia Neviana Ivanova Ivanova, PhD
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